N-acetoxy-2-acetylaminofluorene modification of a deoxyoligonucleotide duplex.
The carcinogen N-acetoxy-2-acetylaminofluorene was reacted with d (CCACGCACC) to form a covalent adduct with attachment at the single guanine. The sample was purified, mixed 1:1 with d (GGTGCGTGG) and studied by thermal denaturation experiments. The Tm for the mixture was 35 +/- 3 degrees C, consist...
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| Veröffentlicht in: | Nucleic Acids Res |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
1985
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| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC321921/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4034398/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/13.16.5907 |
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