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N-acetoxy-2-acetylaminofluorene modification of a deoxyoligonucleotide duplex.

The carcinogen N-acetoxy-2-acetylaminofluorene was reacted with d (CCACGCACC) to form a covalent adduct with attachment at the single guanine. The sample was purified, mixed 1:1 with d (GGTGCGTGG) and studied by thermal denaturation experiments. The Tm for the mixture was 35 +/- 3 degrees C, consist...

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Bibliografski detalji
Glavni autori: Sanford, D G, Krugh, T R
Format: Artigo
Jezik:Inglês
Izdano: 1985
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC321921/
https://ncbi.nlm.nih.gov/pubmed/4034398
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