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Mechanisms of glucose sensing in the pancreatic β-cell: A computational systems-based analysis
Pancreatic β-cells respond to rising blood glucose by increasing oxidative metabolism, leading to an increased ATP/ADP ratio in the cytoplasm with a subsequent influx of calcium and the eventual secretion of insulin. The mechanisms of glucose sensing in the pancreatic β-cell involve the coupling of...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Landes Bioscience
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3219158/ https://ncbi.nlm.nih.gov/pubmed/21814042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/isl.3.5.16409 |
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