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On the fidelity of DNA polymerase alpha: the influence of alpha-thio dNTPs, Mn2+ and mismatch repair.

The phi X174am16 revertant system has been used to investigate the influence of alpha-thio-dNTPs and of Mn2+ on the fidelity of the 9S DNA polymerase alpha from calf thymus. Upon substituting dGTP by alpha-thio-dGTP during the in vitro replication, a nearly tenfold decrease in the frequency of G:G a...

詳細記述

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書誌詳細
出版年:Nucleic Acids Res
主要な著者: Rienitz, A, Grosse, F, Blöcker, H, Frank, R, Krauss, G
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 1985
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC321898/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2994008/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/13.15.5685
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