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Impact of UGT2B7 (His268Tyr )polymorphism on the outcome of adjuvant epirubicin treatment in breast cancer

INTRODUCTION: Epirubicin is a common adjuvant treatment for breast cancer. It is mainly eliminated after glucuronidation through uridine diphosphate-glucuronosyltransferase 2B7 (UGT2B7). The present study aimed to describe the impact of the UGT2B7(His268Tyr )polymorphism on invasive disease-free sur...

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Bibliografiske detaljer
Main Authors: Parmar, Sumit, Stingl, Julia Carolin, Huber-Wechselberger, Ariana, Kainz, Alexander, Renner, Wilfried, Langsenlehner, Uwe, Krippl, Peter, Brockmöller, Jürgen, Haschke-Becher, Elisabeth
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218946/
https://ncbi.nlm.nih.gov/pubmed/21658222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2894
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