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Defective response of CD4(+ )T cells to retinoic acid and TGFβ in systemic lupus erythematosus
INTRODUCTION: CD25(+ )FOXP3(+ )CD4(+ )regulatory T cells (Tregs) are induced by transforming growth factor β (TGFβ) and further expanded by retinoic acid (RA). We have previously shown that this process was defective in T cells from lupus-prone mice expressing the novel isoform of the Pbx1 gene, Pbx...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3218921/ https://ncbi.nlm.nih.gov/pubmed/21708033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3387 |
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