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Neuroinflammation and tumor necrosis factor signaling in the pathophysiology of Alzheimer’s disease

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that affects nearly one in two individuals over 90 years of age. Its neuropathological hallmarks are accumulation of extraneuronal plaques of amyloid-beta (Aβ), the presence of neurofibrillary tangles formed by aberrantly hyperphos...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: McAlpine, Fiona E, Tansey, Malú G
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218716/
https://ncbi.nlm.nih.gov/pubmed/22096345
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