TLR-mediated B cell activation results in ectopic CLIP expression that promotes B cell-dependent inflammation

Infectious pathogens produce compounds called Toll ligands that activate TLRs on lymphocytes. Acute activation triggered by certain TLRs appears to “jump start” the innate immune response, characterized by the release of inflammatory cytokines and cellular expansion. In some individuals, there is a...

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Detalhes bibliográficos
Main Authors: Newell, M. K., Tobin, R. P., Cabrera, J. H., Sorensen, M. B., Huckstep, A., Villalobos-Menuey, E. M., Burnett, M., McCrea, E., Harvey, C. P., Buddiga, A., Bar-Or, A., Freedman, M. S., Nalbantoglu, J., Arbour, N., Zamvil, S. S., Antel, J. P.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Leukocyte Biology 2010
Assuntos:
Inflammation, Extracellular Mediators, & Effector Molecules
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218675/
https://ncbi.nlm.nih.gov/pubmed/20631258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0410237
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