Wird geladen...
Pre-existing soft modes of motion uniquely defined by native contact topology facilitate ligand binding to proteins
Modeling protein flexibility constitutes a major challenge in accurate prediction of protein–ligand and protein–protein interactions in docking simulations. The lack of a reliable method for predicting the conformational changes relevant to substrate binding prevents the productive application of co...
Gespeichert in:
| Hauptverfasser: | , , , |
|---|---|
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Wiley Subscription Services, Inc., A Wiley Company
2011
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3218357/ https://ncbi.nlm.nih.gov/pubmed/21826755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.711 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|