Simulations of the Alternating Access Mechanism of the Sodium Symporter Mhp1

Sodium coupled cotransporters of the five-helix inverted repeat (5HIR) superfamily use an alternating access mechanism to transport a myriad of small molecules across the cell membrane. One of the primary steps in this mechanism is the conformational transition from a state poised to bind extracellu...

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Main Authors: Adelman, Joshua L., Dale, Amy L., Zwier, Matthew C., Bhatt, Divesh, Chong, Lillian T., Zuckerman, Daniel M., Grabe, Michael
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2011
Assuntos:
Channels and Transporters
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218348/
https://ncbi.nlm.nih.gov/pubmed/22098738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.09.061
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