ロード中...
Efficient Atomistic Simulation of Pathways and Calculation of Rate Constants for a Protein–Peptide Binding Process: Application to the MDM2 Protein and an Intrinsically Disordered p53 Peptide
The characterization of protein binding processes — with all of the key conformational changes — has been a grand challenge in the field of biophysics. Here, we have used the weighted ensemble path sampling strategy to orchestrate molecular dynamics simulations, yielding atomistic views of protein–p...
保存先:
| 出版年: | J Phys Chem Lett |
|---|---|
| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
|
| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5008990/ https://ncbi.nlm.nih.gov/pubmed/27532687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpclett.6b01502 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|