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Direct observations of conformational distributions of intrinsically disordered p53 peptides using UV Raman and explicit solvent simulations

We report the first experimental measurements of Ramachandran Ψ-angle distributions for intrinsically disordered peptides: the N-terminal peptide fragment of tumor suppressor p53 and its P27 mutant form. To provide atomically detailed views of the conformational distributions, we performed classical...

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Detaylı Bibliyografya
Asıl Yazarlar: Xiong, Kan, Zwier, Matthew C., Myshakina, Nataliya S., Burger, Virginia M., Asher, Sanford A., Chong, Lillian T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161171/
https://ncbi.nlm.nih.gov/pubmed/21528875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp112235d
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