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Direct observations of conformational distributions of intrinsically disordered p53 peptides using UV Raman and explicit solvent simulations
We report the first experimental measurements of Ramachandran Ψ-angle distributions for intrinsically disordered peptides: the N-terminal peptide fragment of tumor suppressor p53 and its P27 mutant form. To provide atomically detailed views of the conformational distributions, we performed classical...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3161171/ https://ncbi.nlm.nih.gov/pubmed/21528875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp112235d |
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