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A Conformational Transition in the Myosin VI Converter Contributes to the Variable Step Size

Myosin VI (MVI) is a dimeric molecular motor that translocates backwards on actin filaments with a surprisingly large and variable step size, given its short lever arm. A recent x-ray structure of MVI indicates that the large step size can be explained in part by a novel conformation of the converte...

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Détails bibliographiques
Auteurs principaux: Ovchinnikov, V., Cecchini, M., Vanden-Eijnden, E., Karplus, M.
Format: Artigo
Langue:Inglês
Publié: The Biophysical Society 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218336/
https://ncbi.nlm.nih.gov/pubmed/22098742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.09.044
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