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Free energy of conformational transition paths in biomolecules: The string method and its application to myosin VI
A set of techniques developed under the umbrella of the string method is used in combination with all-atom molecular dynamics simulations to analyze the conformation change between the prepowerstroke (PPS) and rigor (R) structures of the converter domain of myosin VI. The challenges specific to the...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Institute of Physics
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3060930/ https://ncbi.nlm.nih.gov/pubmed/21361558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.3544209 |
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