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Experimentally Derived Structural Constraints for Amyloid Fibrils of Wild-Type Transthyretin
Transthyretin (TTR) is a largely β-sheet serum protein responsible for transporting thyroxine and vitamin A. TTR is found in amyloid deposits of patients with senile systemic amyloidosis. TTR mutants lead to familial amyloidotic polyneuropathy and familial amyloid cardiomyopathy, with an earlier age...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3218328/ https://ncbi.nlm.nih.gov/pubmed/22098747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.10.009 |
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