Impaired Mitochondrial Biogenesis Precedes Heart Failure in Right Ventricular Hypertrophy in Congenital Heart Disease

BACKGROUND: The outcome of the surgical repair in congenital heart disease (CHD) correlates with the degree of myocardial damage. In this study we determined whether mitochondrial DNA depletion is a sensitive marker of right ventricular (RV) damage and whether impaired mitochondrial DNA (mtDNA) repl...

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Bibliographic Details
Main Authors: Karamanlidis, Georgios, Bautista-Hernandez, Victor, Fynn-Thompson, Francis, Nido, Pedro del, Tian, Rong
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218261/
https://ncbi.nlm.nih.gov/pubmed/21840936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.111.961474
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