Improving T cell therapy for relapsed EBV-negative Hodgkin’s Lymphoma by targeting upregulated MAGE-A4

RATIONALE: Patients with Hodgkin’s Lymphoma (HL) relapsing after hematopoietic stem cell transplant (HSCT) have limited options for long-term cure. We have shown that infused cytotoxic T cells (CTL) targeting Epstein Barr virus (EBV)-derived proteins induced complete remissions in EBV+ HL patients....

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Hoofdauteurs: Cruz, Conrad R., Gerdemann, Ulrike, Leen, Ann M., Shafer, Jessica A., Ku, Stephanie, Tzou, Benjamin, Horton, Terzah M., Copeland, Amanda, Younes, Anas, Rooney, Cliona M., Heslop, Helen E., Bollard, Catherine M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218253/
https://ncbi.nlm.nih.gov/pubmed/21908573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-1873
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