Improving T cell therapy for relapsed EBV-negative Hodgkin’s Lymphoma by targeting upregulated MAGE-A4

RATIONALE: Patients with Hodgkin’s Lymphoma (HL) relapsing after hematopoietic stem cell transplant (HSCT) have limited options for long-term cure. We have shown that infused cytotoxic T cells (CTL) targeting Epstein Barr virus (EBV)-derived proteins induced complete remissions in EBV+ HL patients....

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Detalhes bibliográficos
Main Authors: Cruz, Conrad R., Gerdemann, Ulrike, Leen, Ann M., Shafer, Jessica A., Ku, Stephanie, Tzou, Benjamin, Horton, Terzah M., Copeland, Amanda, Younes, Anas, Rooney, Cliona M., Heslop, Helen E., Bollard, Catherine M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218253/
https://ncbi.nlm.nih.gov/pubmed/21908573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-1873
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