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Polarity Inversion of Donor-Acceptor Cyclopropanes: Disubstituted δ-Lactones via Enantioselective Iridium Catalysis

The coupling of carbonyl electrophiles at the donor position of donor-acceptor cyclopropanes is described, representing an inversion of polarity with respect to conventional reactivity modes displayed by these reagents. Specifically, upon exposure of donor-acceptor cyclopropanes to alcohols in the p...

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Detalhes bibliográficos
Main Authors: Moran, Joseph, Smith, Austin G., Carris, Ryan M., Johnson, Jeffrey S., Krische, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218199/
https://ncbi.nlm.nih.gov/pubmed/22026505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2090993
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