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Evaluation of bioactive sphingolipids in 4-HPR-resistant leukemia cells
BACKGROUND: N-(4-hydroxyphenyl)retinamide (4-HPR, fenretinide) is a synthetic retinoid with potent pro-apoptotic activity against several types of cancer, but little is known regarding mechanisms leading to chemoresistance. Ceramide and, more recently, other sphingolipid species (e.g., dihydrocerami...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3218121/ https://ncbi.nlm.nih.gov/pubmed/22061047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-477 |
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