Clinical and Genetic Determinants of Warfarin Pharmacokinetics and Pharmacodynamics during Treatment Initiation

Variable warfarin response during treatment initiation poses a significant challenge to providing optimal anticoagulation therapy. We investigated the determinants of initial warfarin response in a cohort of 167 patients. During the first nine days of treatment with pharmacogenetics-guided dosing, S...

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Detalhes bibliográficos
Main Authors: Gong, Inna Y., Schwarz, Ute I., Crown, Natalie, Dresser, George K., Lazo-Langner, Alejandro, Zou, GuangYong, Roden, Dan M., Stein, C. Michael, Rodger, Marc, Wells, Philip S., Kim, Richard B., Tirona, Rommel G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218053/
https://ncbi.nlm.nih.gov/pubmed/22114699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027808
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