Arthrogenicity of type II collagen monoclonal antibodies associated with complement activation and antigen affinity

BACKGROUND: The collagen antibody-induced arthritis (CAIA) model, which employs a cocktail of monoclonal antibodies (mAbs) to type II collagen (CII), has been widely used for studying the pathogenesis of autoimmune arthritis. In this model, not all mAbs to CII are capable of inducing arthritis becau...

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Hlavní autoři: Koobkokkruad, Thongchai, Kadotani, Tatsuya, Hutamekalin, Pilaiwanwadee, Mizutani, Nobuaki, Yoshino, Shin
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3217917/
https://ncbi.nlm.nih.gov/pubmed/22054174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-9255-8-31
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