Suppression of antibody-mediated arthritis in mice by Fab fragments of the mediating antibodies

BACKGROUND AND PURPOSE: Fab fragments (Fabs) of antibodies maintain the ability to bind specific antigens, but lack the binding site for complement as well as the site for binding to receptors on effector cells, such as macrophages that play an important role in inflammation. In the present study, w...

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Detalhes bibliográficos
Main Authors: Yoshino, S, Sasahara, M, Hutamekalin, Pilaiwanwadee, Yamaki, K, Mizutani, N, Kuramoto, H
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2010
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000659/
https://ncbi.nlm.nih.gov/pubmed/20946119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00938.x
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