Erythropoietin both protects from and reverses experimental diabetic neuropathy

Erythropoietin (EPO) possesses generalized neuroprotective and neurotrophic actions. We tested the efficacy of recombinant human EPO (rhEPO) in preventing and reversing nerve dysfunction in streptozotocin (STZ)-induced diabetes in rats. Two days after STZ [60 mg/kg of body weight (b.w.), i.p.], diab...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Bianchi, Roberto, Buyukakilli, Belgin, Brines, Michael, Savino, Costanza, Cavaletti, Guido, Oggioni, Norberto, Lauria, Giuseppe, Borgna, Monica, Lombardi, Raffaella, Cimen, Burak, Comelekoglu, Ulku, Kanik, Arzu, Tataroglu, Cengiz, Cerami, Anthony, Ghezzi, Pietro
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC321765/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14718663/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0307823100
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