Erythropoietin mediates tissue protection through an erythropoietin and common β-subunit heteroreceptor

The cytokine erythropoietin (Epo) is tissue-protective in preclinical models of ischemic, traumatic, toxic, and inflammatory injuries. We have recently characterized Epo derivatives that do not bind to the Epo receptor (EpoR) yet are tissue-protective. For example, carbamylated Epo (CEpo) does not s...

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發表在:Proc Natl Acad Sci U S A
Main Authors: Brines, Michael, Grasso, Giovanni, Fiordaliso, Fabio, Sfacteria, Alessandra, Ghezzi, Pietro, Fratelli, Maddalena, Latini, Roberto, Xie, Qiao-wen, Smart, John, Su-Rick, Chiao-ju, Pobre, Eileen, Diaz, Deborah, Gomez, Daniel, Hand, Carla, Coleman, Thomas, Cerami, Anthony
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2004
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC522054/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15456912/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0406491101
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