Erythropoietin mediates tissue protection through an erythropoietin and common β-subunit heteroreceptor

The cytokine erythropoietin (Epo) is tissue-protective in preclinical models of ischemic, traumatic, toxic, and inflammatory injuries. We have recently characterized Epo derivatives that do not bind to the Epo receptor (EpoR) yet are tissue-protective. For example, carbamylated Epo (CEpo) does not s...

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Detalhes bibliográficos
Main Authors: Brines, Michael, Grasso, Giovanni, Fiordaliso, Fabio, Sfacteria, Alessandra, Ghezzi, Pietro, Fratelli, Maddalena, Latini, Roberto, Xie, Qiao-wen, Smart, John, Su-Rick, Chiao-ju, Pobre, Eileen, Diaz, Deborah, Gomez, Daniel, Hand, Carla, Coleman, Thomas, Cerami, Anthony
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC522054/
https://ncbi.nlm.nih.gov/pubmed/15456912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406491101
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