Erythropoietin both protects from and reverses experimental diabetic neuropathy

Erythropoietin (EPO) possesses generalized neuroprotective and neurotrophic actions. We tested the efficacy of recombinant human EPO (rhEPO) in preventing and reversing nerve dysfunction in streptozotocin (STZ)-induced diabetes in rats. Two days after STZ [60 mg/kg of body weight (b.w.), i.p.], diab...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Bianchi, Roberto, Buyukakilli, Belgin, Brines, Michael, Savino, Costanza, Cavaletti, Guido, Oggioni, Norberto, Lauria, Giuseppe, Borgna, Monica, Lombardi, Raffaella, Cimen, Burak, Comelekoglu, Ulku, Kanik, Arzu, Tataroglu, Cengiz, Cerami, Anthony, Ghezzi, Pietro
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC321765/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14718663/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0307823100
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