Erythropoietin both protects from and reverses experimental diabetic neuropathy

Erythropoietin (EPO) possesses generalized neuroprotective and neurotrophic actions. We tested the efficacy of recombinant human EPO (rhEPO) in preventing and reversing nerve dysfunction in streptozotocin (STZ)-induced diabetes in rats. Two days after STZ [60 mg/kg of body weight (b.w.), i.p.], diab...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Bianchi, Roberto, Buyukakilli, Belgin, Brines, Michael, Savino, Costanza, Cavaletti, Guido, Oggioni, Norberto, Lauria, Giuseppe, Borgna, Monica, Lombardi, Raffaella, Cimen, Burak, Comelekoglu, Ulku, Kanik, Arzu, Tataroglu, Cengiz, Cerami, Anthony, Ghezzi, Pietro
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2004
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC321765/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14718663/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0307823100
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