Increased primary tumor growth in mice null for β3- or β3/β5-integrins or selectins
Expression of αvβ3- or αvβ5-integrins and selectins is widespread on blood cells and endothelial cells. Here we report that human tumor cells injected s.c. into mice lacking β3- or β3/β5-integrins or various selectins show enhanced tumor growth compared with growth in control mice. There was increas...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2004
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC321755/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14718670/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0307289101 |
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