Synergistic effects of L- and P-selectin in facilitating tumor metastasis can involve non-mucin ligands and implicate leukocytes as enhancers of metastasis

P-selectin facilitates human carcinoma metastasis in immunodeficient mice by mediating early interactions of platelets with bloodborne tumor cells via their cell surface mucins, and this process can be blocked by heparin [Borsig, L., Wong, R., Feramisco, J., Nadeau, D. R., Varki, N. M. & Varki,...

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Bibliographic Details
Main Authors: Borsig, Lubor, Wong, Richard, Hynes, Richard O., Varki, Nissi M., Varki, Ajit
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2002
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC122341/
https://ncbi.nlm.nih.gov/pubmed/11854515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.261704098
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