Synergistic effects of L- and P-selectin in facilitating tumor metastasis can involve non-mucin ligands and implicate leukocytes as enhancers of metastasis

P-selectin facilitates human carcinoma metastasis in immunodeficient mice by mediating early interactions of platelets with bloodborne tumor cells via their cell surface mucins, and this process can be blocked by heparin [Borsig, L., Wong, R., Feramisco, J., Nadeau, D. R., Varki, N. M. & Varki, A. (...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Borsig, Lubor, Wong, Richard, Hynes, Richard O., Varki, Nissi M., Varki, Ajit
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2002
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122341/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11854515/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.261704098
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