Synergistic effects of L- and P-selectin in facilitating tumor metastasis can involve non-mucin ligands and implicate leukocytes as enhancers of metastasis

P-selectin facilitates human carcinoma metastasis in immunodeficient mice by mediating early interactions of platelets with bloodborne tumor cells via their cell surface mucins, and this process can be blocked by heparin [Borsig, L., Wong, R., Feramisco, J., Nadeau, D. R., Varki, N. M. & Varki, A. (...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Borsig, Lubor, Wong, Richard, Hynes, Richard O., Varki, Nissi M., Varki, Ajit
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2002
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122341/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11854515/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.261704098
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