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MLL 5 protein forms intranuclear foci, and overexpression inhibits cell cycle progression

MLL5 is a mammalian trithorax group (trx-G) gene identified within chromosome band 7q22, a frequently deleted element found in cytogenetic aberrations of acute myeloid malignancies. MLL5 cDNA was linked with the FLAG and V5 tags at the N and C terminus, respectively, and transfected into 293T cells....

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Главные авторы: Deng, Lih-Wen, Chiu, Isaac, Strominger, Jack L.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2004
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC321754/
https://ncbi.nlm.nih.gov/pubmed/14718661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2036345100
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