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Ex vivo expansion of human Tregs specific for alloantigens presented directly or indirectly

Adoptive transfer of regulatory T cells (Tregs) prevents GVHD in experimental animals. Because antigen activation drives Treg function, we measured the frequency, growth requirements, and function of alloantigen-specific (allospecific) Tregs from human blood. When alloantigen was presented directly,...

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Autori principali: Veerapathran, Anandharaman, Pidala, Joseph, Beato, Francisca, Yu, Xue-Zhong, Anasetti, Claudio
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3217366/
https://ncbi.nlm.nih.gov/pubmed/21948174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-02-337097
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