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Interleukin-1 inhibits osmotically-induced calcium signaling and volume regulation in articular chondrocytes

OBJECTIVE: Articular chondrocytes respond to osmotic stress with transient changes in cell volume and the intracellular concentration of calcium ion ([Ca(2+)](i)). The goal of this study was to examine the hypothesis that interleukin-1 (IL-1), a pro-inflammatory cytokine associated with osteoarthrit...

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Autors principals: Pritchard, Scott, Votta, Bartholomew J., Kumar, Sanjay, Guilak, Farshid
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3217044/
https://ncbi.nlm.nih.gov/pubmed/18495501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2008.04.003
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