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Chondroprotective role of the osmotically-sensitive ion channel TRPV4: Age- and sex-dependent progression of osteoarthritis in Trpv4 deficient mice
OBJECTIVES: Mechanical loading significantly influences the physiology and pathology of articular cartilage, although the mechanisms of mechanical signal transduction are not fully understood. Transient receptor potential vanilloid 4 (TRPV4) is a calcium (Ca(++)) permeable ion channel that is highly...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3027356/ https://ncbi.nlm.nih.gov/pubmed/20583100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.27624 |
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