Pre-Treatment of Recombinant Mouse MFG-E8 Downregulates LPS-Induced TNF-α Production in Macrophages via STAT3-Mediated SOCS3 Activation

Milk fat globule-epidermal growth factor factor 8 (MFG-E8) regulates innate immune function by modulating cellular signaling, which is less understood. Herein, we aimed to investigate the direct anti-inflammatory role of MFG-E8 in macrophages by pre-treatment with recombinant murine MFG-E8 (rmMFG-E8...

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Autors principals: Aziz, Monowar, Jacob, Asha, Matsuda, Akihisa, Wu, Rongqian, Zhou, Mian, Dong, Weifeng, Yang, Weng-Lang, Wang, Ping
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3217009/
https://ncbi.nlm.nih.gov/pubmed/22114683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027685
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