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Galectin-3 Mediates Cross-Talk between K-Ras and Let-7c Tumor Suppressor microRNA
BACKGROUND: Galectin-3 (Gal-3) and active (GTP-bound) K-Ras contribute to the malignant phenotype of many human tumors by increasing the rate of cell proliferation, survival, and migration. These Gal-3-mediated effects result from a selective binding to K-Ras.GTP, causing increased nanoclustering in...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3216962/ https://ncbi.nlm.nih.gov/pubmed/22102901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027490 |
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