טוען...
The tumor suppressor microRNA let-7 represses the HMGA2 oncogene
HMGA2, a high-mobility group protein, is oncogenic in a variety of tumors, including benign mesenchymal tumors and lung cancers. Knockdown of Dicer in HeLa cells revealed that the HMGA2 gene is transcriptionally active, but its mRNA is destabilized in the cytoplasm through the microRNA (miRNA) pathw...
שמור ב:
| Main Authors: | , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Cold Spring Harbor Laboratory Press
2007
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1855228/ https://ncbi.nlm.nih.gov/pubmed/17437991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1540407 |
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