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Uncoupling of Retinoic Acid Signaling From Tailbud Development Before Termination of Body Axis Extension
During the early stages of body axis extension, retinoic acid (RA) synthesized in somites by Raldh2 represses caudal fibroblast growth factor (FGF) signaling to limit the tailbud progenitor zone. Excessive RA down-regulates Fgf8 and triggers premature termination of body axis extension, suggesting t...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3216692/ https://ncbi.nlm.nih.gov/pubmed/21538808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.20763 |
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