The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress

Disruptions of the endoplasmic reticulum (ER) that perturb protein folding cause ER stress and elicit an unfolded protein response (UPR) that involves translational and transcriptional changes in gene expression aimed at expanding the ER processing capacity and alleviating cellular injury. Three ER...

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Hauptverfasser: Teske, Brian F., Wek, Sheree A., Bunpo, Piyawan, Cundiff, Judy K., McClintick, Jeanette N., Anthony, Tracy G., Wek, Ronald C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2011
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3216664/
https://ncbi.nlm.nih.gov/pubmed/21917591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-06-0510
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