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β3 Integrin–EGF receptor cross-talk activates p190RhoGAP in mouse mammary gland epithelial cells

Active RhoA localizes to plasma membrane, where it stimulates formation of focal adhesions and stress fibers. RhoA activity is inhibited by p190RhoGAP following integrin-mediated cell attachment to allow sampling of new adhesive environments. p190RhoGAP is itself activated by Src-dependent tyrosine...

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Detalhes bibliográficos
Main Authors: Balanis, Nikolas, Yoshigi, Masaaki, Wendt, Michael K., Schiemann, William P., Carlin, Cathleen R.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3216655/
https://ncbi.nlm.nih.gov/pubmed/21937717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-08-0700
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