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Enhancing apoptosis in TRAIL-resistant cancer cells using fundamental response rules

The tumor necrosis factor related apoptosis-inducing ligand (TRAIL) induces apoptosis in malignant cells, while leaving other cells mostly unharmed. However, several carcinomas remain resistant to TRAIL. To investigate the resistance mechanisms in TRAIL-stimulated human fibrosarcoma (HT1080) cells,...

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Hlavní autoři: Piras, Vincent, Hayashi, Kentaro, Tomita, Masaru, Selvarajoo, Kumar
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3216625/
https://ncbi.nlm.nih.gov/pubmed/22355661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00144
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