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Systems Biology Strategy Reveals PKCδ is Key for Sensitizing TRAIL-Resistant Human Fibrosarcoma

Cancer cells are highly variable and largely resistant to therapeutic intervention. Recently, the use of the tumor necrosis factor related apoptosis-inducing ligand (TRAIL) induced treatment is gaining momentum due to TRAIL’s ability to specifically target cancers with limited effect on normal cells...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Hayashi, Kentaro, Tabata, Sho, Piras, Vincent, Tomita, Masaru, Selvarajoo, Kumar
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4283611/
https://ncbi.nlm.nih.gov/pubmed/25601862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00659
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