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Systems Biology Strategy Reveals PKCδ is Key for Sensitizing TRAIL-Resistant Human Fibrosarcoma

Cancer cells are highly variable and largely resistant to therapeutic intervention. Recently, the use of the tumor necrosis factor related apoptosis-inducing ligand (TRAIL) induced treatment is gaining momentum due to TRAIL’s ability to specifically target cancers with limited effect on normal cells...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Hayashi, Kentaro, Tabata, Sho, Piras, Vincent, Tomita, Masaru, Selvarajoo, Kumar
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4283611/
https://ncbi.nlm.nih.gov/pubmed/25601862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00659
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