A systems biology approach to suppress TNF-induced proinflammatory gene expressions

BACKGROUND: Tumor necrosis factor (TNF) is a widely studied cytokine (ligand) that induces proinflammatory signaling and regulates myriad cellular processes. In major illnesses, such as rheumatoid arthritis and certain cancers, the expression of TNF is elevated. Despite much progress in the field, t...

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Bibliographic Details
Main Authors: Hayashi, Kentaro, Piras, Vincent, Tabata, Sho, Tomita, Masaru, Selvarajoo, Kumar
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3832246/
https://ncbi.nlm.nih.gov/pubmed/24199619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-11-84
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