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In vitro and in vivo efficacy of fluorodeoxycytidine analogs against highly pathogenic avian influenza H5N1, seasonal, and pandemic H1N1 virus infections

Various fluorodeoxyribonucleosides were evaluated for their antiviral activities against influenza virus infections in vitro and in vivo. Among the most potent inhibitors was 2'-deoxy-2'-fluorocytidine (2'-FdC). It inhibited various strains of low and highly pathogenic avian influenza...

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Bibliografiske detaljer
Main Authors: Kumaki, Yohichi, Day, Craig W., Smee, Donald F., Morrey, John D., Barnard, Dale L.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3216401/
https://ncbi.nlm.nih.gov/pubmed/21925541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2011.09.001
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