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In vitro and in vivo efficacy of fluorodeoxycytidine analogs against highly pathogenic avian influenza H5N1, seasonal, and pandemic H1N1 virus infections

Various fluorodeoxyribonucleosides were evaluated for their antiviral activities against influenza virus infections in vitro and in vivo. Among the most potent inhibitors was 2'-deoxy-2'-fluorocytidine (2'-FdC). It inhibited various strains of low and highly pathogenic avian influenza...

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Detalhes bibliográficos
Main Authors: Kumaki, Yohichi, Day, Craig W., Smee, Donald F., Morrey, John D., Barnard, Dale L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3216401/
https://ncbi.nlm.nih.gov/pubmed/21925541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2011.09.001
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