Salmonella enterica Serovar Typhimurium Requires Nonsterol Precursors of the Cholesterol Biosynthetic Pathway for Intracellular Proliferation

We have previously shown that Salmonella enterica serovar Typhimurium infection perturbs the host cholesterol biosynthetic pathway. Here we show that inhibiting the first step of this pathway (3-hydroxy-3-methylglutaryl coenzyme A reductase) reduces the growth of intracellular S. enterica serovar Ty...

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Autors principals: Catron, Drew M., Lange, Yvonne, Borensztajn, Jayme, Sylvester, Matthew D., Jones, Bradley D., Haldar, Kasturi
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
Matèries:
Molecular Pathogenesis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC321618/
https://ncbi.nlm.nih.gov/pubmed/14742551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.2.1036-1042.2004
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