Salmonella enterica Serovar Typhimurium Requires Nonsterol Precursors of the Cholesterol Biosynthetic Pathway for Intracellular Proliferation

We have previously shown that Salmonella enterica serovar Typhimurium infection perturbs the host cholesterol biosynthetic pathway. Here we show that inhibiting the first step of this pathway (3-hydroxy-3-methylglutaryl coenzyme A reductase) reduces the growth of intracellular S. enterica serovar Ty...

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Hlavní autoři: Catron, Drew M., Lange, Yvonne, Borensztajn, Jayme, Sylvester, Matthew D., Jones, Bradley D., Haldar, Kasturi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
Molecular Pathogenesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC321618/
https://ncbi.nlm.nih.gov/pubmed/14742551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.2.1036-1042.2004
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