Salmonella enterica Serovar Typhimurium Requires Nonsterol Precursors of the Cholesterol Biosynthetic Pathway for Intracellular Proliferation

We have previously shown that Salmonella enterica serovar Typhimurium infection perturbs the host cholesterol biosynthetic pathway. Here we show that inhibiting the first step of this pathway (3-hydroxy-3-methylglutaryl coenzyme A reductase) reduces the growth of intracellular S. enterica serovar Ty...

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Detalhes bibliográficos
Main Authors: Catron, Drew M., Lange, Yvonne, Borensztajn, Jayme, Sylvester, Matthew D., Jones, Bradley D., Haldar, Kasturi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC321618/
https://ncbi.nlm.nih.gov/pubmed/14742551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.2.1036-1042.2004
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