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Salmonella enterica Serovar Typhimurium Requires Nonsterol Precursors of the Cholesterol Biosynthetic Pathway for Intracellular Proliferation

We have previously shown that Salmonella enterica serovar Typhimurium infection perturbs the host cholesterol biosynthetic pathway. Here we show that inhibiting the first step of this pathway (3-hydroxy-3-methylglutaryl coenzyme A reductase) reduces the growth of intracellular S. enterica serovar Ty...

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Udgivet i:Infect Immun
Principais autores: Catron, Drew M., Lange, Yvonne, Borensztajn, Jayme, Sylvester, Matthew D., Jones, Bradley D., Haldar, Kasturi
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2004
Fag:
Molecular Pathogenesis
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC321618/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14742551/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.72.2.1036-1042.2004
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