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Haplotype Reconstruction in Large Pedigrees with Untyped Individuals through IBD Inference

Haplotypes, as they specify the linkage patterns between dispersed genetic variations, provide important information for understanding the genetics of human traits. However, haplotypes are not directly obtainable from current genotyping platforms, which pushes extensive investigations of computation...

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Detalhes bibliográficos
Main Authors: Li, Xin, Li, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3216110/
https://ncbi.nlm.nih.gov/pubmed/21923410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2011.0167
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